This study introduces a holistic model integrating factors from the destination country, source country, and the characteristics of medical tourists, forming a cohesive framework to identify the motivators driving medical tourism. Employing a comprehensive domain-based review, the framework categorizes motivation factors into four contexts: High-Quality Medical Services and Infrastructure, Regulatory and Privacy, Financial and Operational, and Proximity factors. This approach differentiates push motivations associated with source countries from pull motivations related to destination countries. The proposed model provides stakeholders in the medical tourism industry with a structured way to segment medical tourists, position their respective countries, and design essential medical facilities. Key findings suggest that patients from Global North countries are driven to Global South by financial and operational factors, while those from Global South often seek medical care in Global South due to cultural, religious, and geographic proximity. Medical tourism to Global North from Global North is largely driven by regulatory or privacy factors while Global South medical tourists visit Global North destinations mostly due to high quality service and infrastructure. The model's practical implications can guide healthcare providers, marketing managers, and policymakers in creating effective strategies to attract and retain medical tourists.