One of the triggers of the pandemic in the corporate sector has been the spree of people resigning from their jobs across the business sectors from 2021. A growing body of research has called attention to the massive number of global resignations during and after pandemic outbreaks, termed the Great Resignation. It is an unprecedented moment in the history of work and employment where the employees are introspecting not on the essential dynamics of work but on why they work. In this article, the phenomenon of the Great Resignation has been explored to discern the impact on employee work behavior and the consequent implications on business. An exploratory study was conducted of the recent research and survey report studies. Findings suggest that the psycho-social and cultural variables are the predominant reason for quitting. Based on the study's findings, organizational implications have been discussed.