The turbulence and permacrisis in today’s business environment require rethinking established organizational leadership approaches to achieve long-term growth and profitability. Drawing on insights from the current literature, coupled with analysis of cases of organizations navigating extreme environmental conditions, this article identifies five foundational principles of longevity-centered leadership (Clarity, Proactivity, Alignment, Co-Creation, and Learning) that enable sustained value creation in tumultuous environments. Rather than introducing new tools, we argue that the effectiveness of leadership frameworks depends on their coherence with these enduring principles. Each principle is examined through conceptual grounding, empirical illustrations, and practical implications. While rooted in exceptional contexts, the findings offer broadly relevant insights for organizations navigating chronic disruption, volatility, and complexity. The article concludes by showing how these principles work as an integrated system and provides a diagnostic lens for guiding leadership action in the permacrisis era.